Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia, most cases with parathyroid adenoma as the underlying pathology. However, when blood and urine calcium levels and PTH are higher than normal in PHPT, t’s important to suspect an ectopic PTH secretion or a parathyroid carcinoma. Intrathyroidal parathyroid cysts are extremely rare cause of severe PHPT.Clinical case: A 36-year-old male presented with dizziness ...

Introduction: Gestational diabetes (GD) is one of the most common complications of pregnancy. Thyroid hormones play an important role in carbohydrate homeostasis, however, their influence on the risk of developing gestational diabetes has shown contradictory results.Objective: To explore whether variations in thyroid function parameters, within the thresholds of normality, can be associated with the risk of developing GD.Material a...

Background: Identifying the etiology of hypoglycemia in a non-diabetic patient is a significant challenge. Hyperinsulinemic hypoglycemia can lead to pancreatectomy in patients with no evident organic disease. Insulin autoimmune syndrome (IAS) or Hirata diseaseand Type B insulin resistance syndrome are the two typesof autoimmune hypoglycemia, with a low worldwide prevalence.Objective: We report two real-lifecases that illustrate each of them.<p class=...

Objective: Prospective observational study in a group of pregnant patients affected by type 1 diabetes (T1DM), that are monitored by the Endocrinology and Pregnancy Unit.Material and Methods: Weevaluated 12 pregnant patients with T1DM in which a FreeStyle Libre Flash Glucose Monitoring Systemwas installed, in addition to their capillary glucose self-control (SMBG), over the past year 2019. Time above range (TAR), time in range (TIR) and time below range ...

Patients with non-alcoholic fatty liver disease (NAFLD) have a higher prevalence of cardiovascular disease, particularly patients with liver fibrosis. Studies have shown a relationship between epicardial fat/coronary calcium and myocardial ischemia.Aim: Quantify epicardial fat and coronary calcium assessed by computed tomography (CT) in patients with NAFLD. Additionally, determine whether patients with hepatic fibrosis quantitatively assessed by liver el...

Introduction: Non-functioningpituitary adenomas (NFPAs) are of benign nature but a sizeable number of NFPAs show aggressive features. Surgery is not always effective in treating NFPAs and thus other therapeutic options are needed. Previous studies have reported that NFPAs express somastostatin receptors (SSTRs) and dopamine receptors (DRDs).Aim: To systematically analyze the expression of SSTRs and DRDs in a large cohort of clinically well-characterized ...

Introduction: Clinical trials indicate that Tolvaptan is safe and effective in the treatment of patients with sustained mild/moderate SIADH-induced euvolemic hyponatremia. Tolvaptan doses are often modified during chronic use. We present the weekly doses of a series of patients on chronic therapy, followed up in outpatient clinic.Methods: Retrospective, cross-sectional. 114 patients receiving tolvaptan for chronic SIADH were followed up in a Hyponatremia...

Introduction: In patients with human immunodeficiency virus (HIV) infection, the prevalence of osteoporosis is higher in comparison with the general population. Anti-retroviral therapy (ART) use seems to be a possible risk factor there is also high prevalence of vitamin D deficiency among people living with HIV.Objectives: To describe bone mineral density (BMD) status in HIV-infected patients as well as its associated risk factors such as vit D levels.</...

Introduction: Ketosis-prone diabetes or Flatbush diabetes has been recognized as a clinical entity since 1984. Is characterized by diabetic ketosis or ketoacidosis occurring soon after the onset of hyperglycemic syntoms (usually poyiuria, polydipsia and weight loss are present for less than 4 weeks). Unlike the insulin dependence seen in type 1 diabetes, after a few weeks (usually 2 to 12 weeks), insulin requeriments decrease, and approximately 70% of patients achieve remissio...

Introduction: NutriScore is a tool designed with the aim of simplifying the information of the nutritional composition obtained from the labelling. It classifies foods into five colors ranging from green (healthier) to red (less healthy). These colors are associated with five letters (A/B/C/D/E).Objective: To examine the nutritional value of foods sold in vending machines of the public hospitals in Community of Madrid (Spain), by calculating the nutrisco...